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Showing posts with label anabolic steroids. Show all posts
Showing posts with label anabolic steroids. Show all posts

Monday, October 20, 2014

Anabolic Steroids : Making Musclemen Infertile

Growing numbers of men are becoming infertile because they take anabolic steroids in their quest for a muscular body, doctors have warned.

Urologists are seeing more and more men whose difficulty in becoming a father is linked to consumption of the muscle-boosting drugs.

Many fit young men who believe they are at the peak of physical perfection don't believe it could be their fault when their wives or girlfriends find it difficult to become pregnant.

They are insulted when it is suggested that they undergo a sperm test, and horrified when the results of those tests show an absence of sperm in the sample.

Such men are then referred to a urologist, and undergo a blood test. If they have been using steroids, they often have what calls deranged levels of sex hormones.

Men who regularly go to the gym should avoid taking steroids to bulk up.

Acne, aggression and an unexplained, orange skin tone akin to a tan are also associated with use of steroids.

It is a very real risk that men who take anabolic steroids will become infertile. It's almost certain that steroids will have an effect of some sort on their fertility and, in the worst-case scenario, that sperm production will stop altogether.

These patients walk through the door looking like Arnold Schwarzenegger in his younger days. They are having fertility problems, and it suddenly becomes obvious where the problem may lie.

Some men who stop taking steroids never regain their reproductive capacity and for others it takes years for normal sperm production to resume.

Monday, August 11, 2014

Public Enemy #1 for Male Fertility: Anabolic Steroids

Did you notice those guys with big muscles at the gym or on the beach? The muscles may be from "just plain old fashioned hard work in the gym" or they could be from using anabolic steroids or performing enhancing drugs (PED). Those that use anabolic steroids or PEDs to build and repair muscle are doing damage to their testicles. These testosterone-based hormones are very bad for men who eventually want to have children. They actually work almost like a contraceptive. When a man is taking anabolic steroids, it is virtually impossible for him to get his partner pregnant.

The use of anabolic steroids historically has been used by athletes in major sports, such as weight lifting, baseball and football. Because these so called "role models" use these drugs, anabolic steroid use or abuse has filtered down and is being used by recreational weight lifters, college and high school athletes, etc.

How do anabolic steroids affect male fertility? Sperm are formed in the body when brain hormones such as luteinizing hormone (LH) and follicle stimulating hormone (FSH) work directly on the testicles. In the testicle, cells called Leydig cells are turned on to produce the male hormone, testosterone. When this occurs, there are very high levels of testosterone that are present in the testicle, although there is a normal amount of testosterone in the blood stream. When men use anabolic steroids, they trick the body into thinking that the testicles DO NOT have to produce testosterone. When this happens, the amount of testosterone in the testicles is extremely low, despite normal or very high levels in the bloodstream. When this situation occurs, follicle stimulating hormone also is not released. This combination causes the testicles to shrink and to produce little if any sperm.

Although use of anabolic steroids can stop sperm production, the good news is that in many cases this problem is reversible. It appears that the longer one uses the steroids and the higher the dosage used, the more likely these become irreversible problems. Once performance enhancing drugs are stopped, sperm production may start again but will return in the ejaculate at the earliest three months after stopping the drugs. In fact, in patients who have used steroids for years, this sometimes may take one to two years before one may see a return in sperm production. After a period of time after stopping the PEDs, sometimes medical therapy can enhance the ability of the body to restart sperm production. This is usually done with human chorionic gonadotropin, or hCG. In certain cases, if hCG alone does not stimulate sperm production, a form of FSH called human menopausal gonadotropin may be added to improve the chances of return of sperm.

Anabolic steroids can cause other health problems that sometimes can be irreversible. These include aggressive behavior, acne, baldness, prominent breasts, liver disease, high blood pressure, heart attack and stroke. In adolescents, it may result in stunted growth and accelerated puberty changes.

PEDs can also cause sexual dysfunction. When the anabolic steroids are stopped, the "sexual rush" is gone and this will cause testosterone levels to crash to virtually zero. This may cause symptoms such as tiredness, loss of energy and loss of sex drive. Testosterone production may return in a few months, however, in certain situations, it may be a permanent problem. Luckily, there is medical treatment for this problem to raise testosterone levels back to the normal range.

So there are lessons to be learned from the abuse of anabolic steroids. The most important point here is if you want to have children at some point in your life, DON'T USE ANABOLIC STEROIDS!!! In addition, stopping anabolic steroids may result in the "crashing of testosterone levels" with associated bad problems related to general health and sexuality.

Friday, July 25, 2014

PENIS ON STEROIDS

Do Steroids Make Your Penis Shrink Or Grow?

This is a common question that many people want to know before they use a cycle of steroids or legal steroids like prohormones. If you don’t know what a prohormone is compared to an active anabolic steroid I suggest you read this article PROHORMONE.  Steroids are only active in the penis if you are under 18 and still in a growth stage.  So, steroids can make your penis small or make your penis bigger if you are under 18 and still growing. This is why we always suggest people who use prohormones or anabolic steroids be over 21 because you can certainly cause some either desirable or undesirable effects based on taking steroids at a young age.

There is some retarded article on the internet that everyone is reposting that discusses the short term effect on libido and your ability to get an erection.

This is for information purposes only, but I feel strongly that people should know about steroids and penis growth because the dangers of steroids are over exaggerated and the benefits can be profound. Dry steroids (ones that don’t convert to estrogen) should in theory increase the size of your penis if you are under 21 and wet steroids (ones that convert to or act like estrogen)  should in theory decrease the size of your penis if you are under 21.  This same mechanism will also have an effect on your height as well. Dry steroids should increase height, while wet steroids should decrease height. If you are under 21 and want to try and increase both height and penis size, I suggest you use a more simple mechanism…Creatine. Creatine will alter the levels of androgens in your body, shifting to a higher DHT level, which can increase your penis size. Creatine has been proven to be safe in teens through the elderly.  Trying to use a steroid or prohormone is way too complicated for the average person, so I implore you to avoid this.

Steroids And Penis Over 21 – NO EFFECTS ON PENIS

Steroids will have no effect on your penis either good or bad if you are over 21 and done growing. The misconception that steroids make your penis shrink is because of their effect on the testicles.  Steroids will certainly make your balls shrink temporarily because when you are on a cycle of steroids your balls shut down production, causing them to shrink slightly.  This effect will reverse itself in 1-2 months after a cycle or you can use post cycle therapy to increase that recovery time.

So, to dispel the age old myth, steroids will not shrink, make smaller, make bigger, increase or alter your penis size. Fortunately or unfortunately, by the time you hit roughly 21 your penis is your penis and nothing will make it bigger or smaller long term. Steroids are only active in penis growth while you are still growing. So stop worrying about your penis and try to tell the world that this myth needs to DIE. With this information you can truly know about your penis on steroids.

Monday, July 21, 2014

Testosterone Therapy vs Anabolic Steroid Use

There is a lot of confusion between the use of anabolic steroids and bioidentical testosterone replacement therapy. For this reason, many people shy away from testosterone therapy, thinking it's a bad thing. Too many people believe that there is no difference between anabolic steroids and bioidentical testosterone replacement. Yet, although anabolic steroids are related to male sex hormones like testosterone, there are some vital differences.

Anabolic steroids are synthetic hormones that are similar in many ways to the androgens, or male sex hormones. Like bioidentical testosterone, the anabolic steroids do promote the growth of skeletal muscle and the secondary male sexual characteristics. Anabolic steroids can be used in productive ways to treat conditions that occur when the body produces abnormally low levels of testosterone. However, bioidentical hormones would actually be a better choice because there are fewer side effects associated with them; those side effects that are possible are less dangerous than those posed by synthetic hormones such as anabolic steroids.

Most people are not as aware of the potential usefulness of anabolic steroids as they are of the potential for abuse. Athletes have been known to use anabolic steroids to develop muscle mass more quickly and become stronger or faster or just plain better at their sport. Of course, the public frowns upon the practice of using anabolic steroids. There are serious and undesirable side effects that can occur as a result of using anabolic steroids to achieve higher levels of athletic performance. For example, abusers can develop liver or kidney tumors, cancer, jaundice, high blood pressure, severe acne, and trembling. Men's testes may shrink and they can develop breasts. In women, anabolic steroid abuse can lead to a growth of facial hair, menstrual changes, and a deepening of the voice. Teens who abuse anabolic steroids may stop growing prematurely and permanently.

Bioidentical testosterone therapy is different from anabolic steroid use or abuse in several ways. First of all, bioidentical hormones are identical in structure and function to the hormones produced by the human body. Synthetic anabolic steroids, in contrast, differ ever-so-slightly from the testosterone produced in the human body. These slight biochemical differences between human testosterone and synthetic androgens are the reason for most of the dangerous side effects associated with the synthetic hormones.

As with most substances, abusing bioidentical testosterone could cause undesirable effects like feminization in men, hair loss and severe acne. Since bioidentical testosterone is typically used to replace testosterone that the body is not producing in adequate quantities either due to disease or old age, it is difficult to abuse. When the body has excess testosterone, it converts it into estrogen and DHT, causing feminizing effects in men. Replacement therapies simply replace missing testosterone; anabolic steroids, however, add more testosterone to the body than it needs, generating some nasty side effects.

Men who are considering bioidentical hormone therapy need to understand that anabolic steroids and bioidentical testosterone are not the same. Bioidentical doctors monitor liver function and lipid levels in men who are using bioidentical testosterone to replace what they are missing. Side effects of this type of therapy do exist, but they are less common than those experienced by men who use anabolic steroids. Bioidentical testosterone can have some important health benefits for aging men. Talking with a bioidentical hormone doctor can help clear up any fears and misunderstandings and help you understand how bioidentical testosterone can improve your overall health as you grow older.

Thursday, July 3, 2014

Anabolic Steroid Abuse Causes, Symptoms and Treatment

Anabolic steroids are drugs such as testosterone or substances that work like testosterone. Doctors prescribe them to treat problems such as delayed puberty and other medical problems that cause the body to make very low amounts of testosterone. Steroids make muscles bigger and bones stronger. They also may cause puberty to start and can help some boys who have a genetic disorder to grow more normally.

Common anabolic steroid medicines include fluoxymesterone (such as Halotestin) and nandrolone (such as Durabolin). In the United States, you need a prescription to get any anabolic steroid. Illegal anabolic steroids are those that people get without a doctor’s prescription.

Some people take legal dietary supplements that have certain steroid hormones also made by the human body. One such drug is dehydroepiandrosterone (DHEA). The body can turn DHEA into other steroid hormones, including testosterone, estrogen, and cortisol. People use it to try to make their muscles bigger. Whether such products actually work has not been proved. But if you take them in large amounts, they can cause the same side effects as anabolic steroids.
Why do some people abuse anabolic steroids?

Some adults and teens use illegal anabolic steroids to lower body fat, get bigger muscles, and increase strength. They use the drugs because they are seeking to improve how well they play sports or how they look.

The dose of illegal anabolic steroids is 10 to 100 times higher than the dose a doctor prescribes for medical problems. People often use more than one of these illegal drugs at the same time. This is called stacking. Or they may take the drugs in a cycle from no drug to a high dose over a period of weeks to months. This is called pyramiding.

Anabolic steroids may be taken as a pill, as a shot into a muscle, or as a gel or cream rubbed on the skin.
What problems can abusing anabolic steroids cause?

Anabolic steroids can cause serious side effects. Some of these effects can be permanent.

    In men, anabolic steroids can:
        Reduce sperm count.
        Shrink the testicles.
        Cause you not to be able to father children.
        Enlarge the breasts.
    In women, anabolic steroids can:
        Increase body hair.
        Make skin rough.
        Decrease breast size.
        Enlarge the clitoris.
        Deepen the voice.
    In both men and women, anabolic steroids can cause:
        Bone growth to stop before it is complete in a teen. The teen may not reach his or her full adult height.
        A heart attack or stroke, even in a very young person.
        High blood pressure.
        Higher levels of bad cholesterol (LDL) and lower levels of good cholesterol (HDL).
        Liver disease and possibly liver cancer. The chance of these problems is higher when steroids are taken as a pill.
        Oily skin and acne.
        Male-pattern hair loss.
        Skin infections that can become severe if the drug was tainted with bacteria.
        Irritability, rage, uncontrolled high energy (mania), or false beliefs (delusions).

People who abuse anabolic steroids can have withdrawal symptoms when they stop taking them. Symptoms include having mood swings, being extremely tired, having no desire to eat, and craving steroids.
How is anabolic steroid abuse diagnosed?

A doctor can often spot a person who is abusing anabolic steroids when that person walks through the door. This is because the medicine makes muscles unusually large. Your doctor may also ask questions about your fitness activities and what kinds of dietary supplements and other substances you use. The doctor may do a physical exam and order urine and blood tests.
How is it treated?

Treatment for abuse of anabolic steroids has not been studied much. Doctors usually advise:

    Treatment in a program that includes medicines for withdrawal symptoms and other health problems.
    Treatment in a hospital, if withdrawal symptoms are severe.
    Individual or family counseling.

Thursday, June 26, 2014

Effects of Steroids on the Male and Female Reproductive Systems

Anabolic steroids can have adverse effects on the male and female reproductive systems. Females might experience more severe effects when taking testosterone because it is produced in small amounts in the female body, making it a foreign substance for women. Effects of steroids in both sexes vary.

Visible Effects
Some side effects of steroid use will be visible to the naked eye. Men can experience breast growth beyond the muscular buildup of the chest muscles. In addition, the testicles might shrink. Men might also notice changes in hair growth patterns and they might lose hair. Women can might develop excess facial hair or lose hair from their head. In women, the clitoris might become unnaturally large while the breasts may lose some of their natural size. Women's voices often become deeper as a result of steroid use.

Hormonal Changes
Hormonal changes resulting from the use of steroids can affect the steroid user. Men can experience longer erections or a higher frequency of erections yet a decrease in sperm production, resulting in sterility. Men might also find that they are impotent and have a problem urinating. According to Concepts of Chemical Dependency, prostate cancer has been found in rare instances. It is possible for women to interruption of their menstrual cycle from steroid use. In addition, women can develop infertility issues as well. Both sexes might experience changes in sex drive, either an increase in desire or a loss of desire. These hormonal changes in the body can increase the amount of acne on the user as well.

Lasting Effects
Many of the side effects of steroid use are irreversible. The development of reproductive cancers affects steroid users for the rest of their lives. In addition, women might continue to suffer from hair loss. In women, the clitoris might never return to normal size. For men, the enlargement of the breasts can be permanent with only surgical removal returning the breasts to normal size. The longer a person uses steroids, the longer it will take for their side effects to go away.

Tuesday, June 10, 2014

Anabolic steroids making musclemen infertile

Growing numbers of men are becoming infertile because they take anabolic steroids in their quest for a muscular body, doctors have warned.

Urologists are seeing more and more men whose difficulty in becoming a father is linked to consumption of the muscle-boosting drugs.

Steve Payne, a consultant urologist at the Manchester Royal Infirmary and a council member of the British Association of Urological Surgeons, said: "Many fit young men who believe they are at the peak of physical perfection don't believe it could be their fault when their wives or girlfriends find it difficult to become pregnant.

"They are insulted when it is suggested that they undergo a sperm test, and horrified when the results of those tests show an absence of sperm in the sample."

Such men are then referred to a urologist, and undergo a blood test. If they have been using steroids, they often have what Payne calls deranged levels of sex hormones.

Men who regularly go to the gym should avoid taking steroids to bulk up, Payne added.

Acne, aggression and an unexplained, orangey skin tone akin to a tan are also associated with use of steroids.

Dr Allan Pacey, a senior lecturer in andrology at Sheffield University, warned: "It is a very real risk that men who take anabolic steroids will become infertile. It's almost certain that they [the steroids] will have an effect of some sort on their fertility and, in the worst-case scenario, that sperm production will stop altogether.

"These patients walk through the door looking like Arnold Schwarzenegger in his younger days. They are having fertility problems, and it suddenly becomes obvious where the problem may lie."

Some men who stop taking steroids never regain their reproductive capacity and for others it takes years for normal sperm production to resume, Pacey added.

Thursday, April 17, 2014

Anabolic Steroids and Infertility

Anabolic Steroids are synthetic substances similar to the male sex hormone testosterone. If used consistently from a young age they can be detrimental to the users health because they upset the body's hormonal balance.

Anabolic Steroids are known to have a variety of harmful side effects, are out of bounds for athletes and users are required to only take them under prescription of a medical doctor. Yet many people take them for the short term benefits they provide - for athletes to improve performance or to enhance physical appearance.

These drugs are often sold on the black market and because their short term benefits are so attractive users tend to ignore the dangerous and possible long term side effects. Users do not consider the effects these substances may have on their fertility health.
   

 Medical Benefits

Steroids aren't only used for bulking up but can be prescribed for legitimate medical reasons. Your medical practioner is well aware of the side effects and will prescribe a dosage with this in mind to cater for your particular situation.


 Some of the medical uses are:

    Men with too little testosterone - Whether it's due to an accident or a disease; such as testicular cancer, some men have to have their testicles removed.Their bodies will no longer be able to produce testosterone. They will be given prescribed oral anabolic steroids to replace the testosterone.

    People with chronic illnesses, such as cancer or even AIDS can use anabolic steroids to stimulate their appetite and help build muscle.
    Pituitary problems -  Steroids can help adolescent males with pituitary problems. When the pituitary gland malfunctions, the brain signals to the testes may not function correctly and the testes therefore does not produce testosterone. Boys suffering from this condition can be prescribed steroids at the appropriate age, as per his doctor. This treatment will allow them to develop secondary sexual characteristics, such as a deepening of the voice, growth spurts and pubic and facial hair.

Anabolic Steroids and fertility

There are a number of side effects users will experience when taking these substances. Some are short term and others may have long term side effects. Unfortunately any side effects will in most cases also effect the male fertility health. Some of these side effects can include:

Short term effects

    Puffiness and swelling in the face and neck due to increased water retention.
    Development of breast tissue in males.
    Increased risk of injury to muscles and joints.
    Increase in muscle mass.
    Heightened aggression, sleeping disorders, anxiety and irritability.
    Stunted growth if taken during adolescent growth spurts due to skeletal maturation and accelerated puberty changes.
    

Long term effects

    Growth of breasts due to the high level of testosterone some of which the body converts to oestrogen.
    Increased erectile dysfunction and shrinking testicles.
    Heart and liver disease - some steroids are toxic to the liver.
    Kidney disease due to the increase in toxins to be broken down.
    Aggressive behaviour and depression.
    Jaundice from high levels of steroids - affects liver function.
    Increased blood pressure.
    Prostate enlargement.


Anabolic Steroids and male infertility are often linked due to the effects on the body as mentioned here.  Any increased toxins in the body have the potential to affect the sperm being produced.

A semen analysis will give a good indication of the health of the sperm if a male has used steroids previously and is now having difficulty with infertility. A low sperm count will also be detected by going for a semen analysis.

Fortunately medical technology and advancement in procedures such as sperm washing as well as ICSI - Intra-Cytoplasmic Sperm Injection could assist men whose fertility may have been affected by the usage of Steroids.

Your doctor will be able to advise you on using an Assisted Reproductive Technology (ART) procedure in the event of being diagnosed with infertility due to this usage.

Tuesday, April 1, 2014

HMG: The Miracle Fertility Med?

When we administer certain hormones into our bodies, various cells and organs have the ability to sense this. Your body 'sees' this increase in testosterone or similar molecules and as a result it can sense that it is in a higher concentration than what would be normal in the blood. As a result, it will shut down its own testosterone production. There are various mechanisms involved in this, but an important one is the cessation in production of luteinizing hormone (LH) and follicle stimulating hormone (FSH), produced by the pituitary gland. These hormones are required for the testes to be stimulated to produce testosterone but also play a role in sperm production.

From a blood-testosterone aspect this all seems okay to us, sure we have shut down natural testosterone production, but we still have testosterone in us; right? Well, one of the big problems with regards to fertility is that the testes do not work like that. The Leydig cells in the testes produce testosterone when stimulated by LH. Testosterone is released from these cells which are in close proximity to the Sertoli cells. When Sertoli cells see a high concentration of testosterone, they are stimulated to produce and mature sperm by the process of spermatogenesis. A high blood concentration of testosterone will not do this job. Thus administering anabolic androgenic steroids (AAS) will shut down natural testosterone production which will in turn slow down (and eventually near turn off) the proper formation and maturation of sperm. Thus infertility is a serious issue with use of anabolic steroids.

Classically, HCG has been seen to rectify this problem in males. HCG is an LH analogue – it 'looks' like LH to the body and so it can stimulate the Leydig cells to produce testosterone and in turn, hopefully, restore fertility. In some cases this will occur, and many people have had success from HCG therapy relating to infertility. However, the response is not robust and certainly with longer shut-down periods, many often find the use of HCG (even in combination with other post cycle therapy (PCT) medicines such as clomifene (aka clomid) and tamoxifen (aka nolvadex), etc) to not be effective at restoring fertility.

Furthermore, what HCG lacks is to produce the important effects that FSH inflicts upon fertility. FSH, despite its name, is important in male fertility in two main pathways. The first thing it does is to enhance the action of LH, by increasing the amount of protein that will 'see' testosterone in the Sertoli cells. The more easily these cells can see testosterone, the more likely spermatogenesis will occur. Secondly, FSH enhances the maturation of sperm by effects on their primary division. These are two important aspects of the role of FSH in the male testes that HCG is not optimal in promoting.

HMG, or its full name Human Menopausal Gonadotropin, bears similarities to HCG in that while HCG is similar to human LH, HMG contains actual LH. Additionally (and crucially) though, HMG also contains purified FSH. The combination of these two hormones perform the effects described above: induction of natural testosterone production by Leydig cells, and subsequent formation and maturation of sperm cells. The result is improved and potentially recovered fertility for the male concerned.

Does HMG really work?
So often we hear about various different drugs and the science for them is sound, but real world evidence is lacking. There are a few studies performed on HMG over the last 25 years, and I would like to draw your attention to two of these studies, pointing out a few key details. The first goes back to 1985 by Ley & Leonard and is an important study as it looks at males who had previously encountered anabolic steroids treatment (treatment for low hormone levels including mainly testosterone). This study is available online and I encourage you to read it in more detail than the brief summary I will provide here.

They looked at 13 hypogonadotropic men all of who had undetectable levels of LH/FSH, lower than normal levels of testosterone and azoospermia, thus were unable to currently conceive. Obviously with the low hormonal levels there were issues with libido as well. Furthermore, there were instances where upon testis biopsies, Leydig cells were completely absent. Despite this, all 13 men responded to treatment with HCG with increasing testosterone levels. However, upon addition of HMG treatment, most men saw a further increase in testosterone, sometimes very large. HCG was able to increase sperm counts in most men slightly; however, only upon addition of HMG were sperm counts above 'normal' fertility levels (i.e. 20 million per ml) observed. The study indicates that the addition of HMG therapy surpasses any level that HCG treatment could achieve alone. Admittedly this is a particular subset of men who have medical conditions and abnormal hormone issues, but the results are interesting nonetheless.

The second is more recent by Buchter et al in 1998. This is even more interesting from the point of view that it looks at three times the number of cases as the previous study and in a different manner. Again, this study can be found online and I encourage you to read it. The most interesting result you could take away from this study is that in the group of men treated who suffered from hypopituitarism, all 21 treated with HCG/HMG achieved spermatogenesis and a large proportion (81%) was able to successfully achieve pregnancies. The discussion of this article is most interesting as it raises the points from its own study and the literature that many in the field believe that to achieve spermatogenesis and pregnancy in a gonadotropin-compromised individual requires combinational therapy of HCG and HMG. The important point to note is that HCG is not sufficient alone in many cases.

Given the fact that other studies point to HMG increasing endogenous testosterone further than HCG can, as those who have relatively 'normal' pituitaries but have compromised their function due to AAS use, it would be wise to consider the use of HMG. This would not only be for purposes of fertility, but to induce natural testosterone levels back to normal values when they have been suppressed. Treatment in this latest study was the use of HCG twice per week at 1000-2500IU per dose (Mon-Fri) and HMG three times per week at 75-150IU (Mon-Wed-Fri). Thus for bodybuilders seeking to regain fertility, spermatogenesis and restore natural testosterone levels but wishing to keep costs down, a weekly dose of the lower ends should be employed for at least one month.

A schedule would involve:
Monday: 1000-1500IU HCG + 75IU HMG
Wednesday: 75IU HMG
Friday: 1000-1500IU HCG + 75IU HMG

Depending on the amount of suppression this cycle may need to be lengthened for a further period.

Thursday, March 6, 2014

Anabolic Steroids and Muscles

Anabolic steroids, known technically as anabolic-androgen steroids or colloquially as "steroids" (or even "roids"), are drugs that mimic the effects of testosterone and dihydrotestosterone in the body. They increase protein synthesis within cells, which results in the buildup of cellular tissue (anabolism), especially in muscles. Anabolic steroids also have androgenic and masculinity-enhancing properties, including the development and maintenance of masculine characteristics such as the growth of the vocal cords, testicles and body hair (secondary sexual characteristics). Anabolic-androgenic steroids were first isolated, identified and synthesized in the 1930's, and are now used therapeutically in medicine to induce bone growth, stimulate appetite, induce male puberty and treat chronic wasting conditions, such as cancer and AIDS. Anabolic steroids also increase muscle mass and physical strength, and are therefore used by athletes and bodybuilders alike to enhance strength or physique. Known side effects include harmful changes in cholesterol levels (increased Low density lipoprotein and decreased High density lipoprotein), acne, high blood pressure and liver damage. Some of these effects can be mitigated by taking supplemental drugs.
Mechanism of action

The pharmacodynamics of anabolic steroids are unlike peptide hormones. Water-soluble peptide hormones cannot penetrate the fatty cell membrane, and only indirectly affect the nucleus of target cells through their interaction with the cell’s surface receptors. However, as fat-soluble hormones, anabolic steroids are membrane-permeable, and influence the nucleus of cells by direct action. The pharmacodynamic action of anabolic steroids begins when the exogenous hormone penetrates the membrane of the target cell and binds to an androgen receptor located in the cytoplasm of that cell. From there, the compound hormone-receptor diffuses into the nucleus, where it either alters the expression of genes or activates processes that send signals to other parts of the cell. Different types of anabolic steroids bind to the androgen receptor with different affinities, depending on their chemical structure. Some anabolic steroids such as methandrostenolone bind weakly to this receptor in vitro, but still exhibit androgenic effects in vivo. The reason for this discrepancy is not known. The effect of anabolic steroids on muscle mass is caused in at least two ways: first, they increase the production of proteins; second, they reduce recovery time by blocking the effects of the stress hormone cortisol on muscle tissue, so that catabolism of muscle is greatly reduced. Some hypothesize that this reduction in muscle breakdown may occur by way of anabolic steroids inhibiting the action of other steroid hormones called glucocorticoids, which promote the breakdown of muscles. Anabolic steroids also affect the number of cells that develop into fat-storage cells by instead favoring cellular differentiation into muscle cells. Additionally, anabolic steroids can decrease fat by increasing basal metabolic rate (BMR), since an increase in muscle mass increases BMR.
Physical effects

Anabolic steroids are testosterone and dihydrotestosterone hormone mimics that stimulate anabolism, specifically protein synthesis and muscle hypertrophy. Due to its similarity to the male sex hormones, using anabolic steroids can result in masculinization of women and changes to secondary sex characteristics of men. This makes steroids attractive to those wishing to alter their appearance, particularly for body building. Further negative side effects of anabolic steroids include stunted growth in adolescents, increase in cholesterol levels, high blood pressure, acne, liver damage and changes to the left ventricle of the heart, not to mention potential psychiatric issues. Despite these side effects, anabolic steroids can be used therapeutically to stimulate bone growth and appetite, and treat chronic wasting conditions associated with cancer and AIDS, though at much lower dosages than those used for performance enhancement.
Steroid abuse

Abuse of anabolic steroids differs from the abuse of other illicit substances, because the initial use of anabolic steroids is motivated not by the immediate euphoria that accompanies other abused drugs such as cocaine, heroin and marijuana, but by the user's desire to change their appearance and performance, characteristics of great importance to adolescents. These effects can boost confidence and strength, leading the user to overlook the potential serious long-term damage that these substances can cause. Due to the unfair advantage given to athletes and competitors who use anabolic steroids, all major sports associations have banned their use.

While anabolic steroids can enhance certain types of performance or appearance, they are dangerous drugs, and when used inappropriately, they can cause a host of severe, long-lasting and often irreversible negative health consequences. For example, they can stunt the height of growing adolescents, masculinize women and alter sex characteristics of men. Anabolic steroids can also lead to premature heart attacks, strokes, liver tumors, kidney failure and serious psychiatric problems. In addition, because steroids are often injected, users risk contracting or transmitting HIV or hepatitis.

Tuesday, February 18, 2014

Deca Durabolin Improves Immune Function

Deca Durabolin, which is also known as Deca and Nandrolone decanoate, is a popular anabolic steroid that is commonly recommended to provide dramatic relief to HIV/AIDS patients and use of this steroid is associated with immune system enhancements. Belonging to the category of anabolic-androgenic steroids and classified as a 2.16 anabolic steroid, it has the ability of stimulating endurance and muscle function gains and promoting muscle growth and size to a significant extent.

It is also beneficial to mask minor joint pain and old nagging injuries and for reducing the inflammation of soft tissues; Deca is also used for the development and maintenance of masculine (secondary sexual) characteristics, including growth of the vocal cords, testicles, and body hair.

Deca Durabolin Improves Immune Function

One of the biggest benefits why Deca Durabolin is extremely popular with sportsmen and fitness conscious people, especially those looking for immune function improvements, is that it improves cell-mediated immune response and improves the activity of macrophages besides reducing the incidence of post-operative infection. It is equally effective in improving immune function, like increasing CD8+ (Cytotoxic cells with CD8 surface protein) count that is highly correlative with improved survival in HIV.

In addition to this, the use of this anabolic steroid is characterized by significant anabolic effects and minimal androgenic side effects. The fact that the side effects of other steroids and performance enhancing drugs like gynecomastia and problems with liver enzymes, blood pressure, or cholesterol levels are rarely seen with the use of this drug means that it is best for even those who are prone to such side effects.

Deca is commonly stacked with Dianabol, Anadrol, and Sustanon and is best known for its abilities to promote good muscle size and strength gains while reducing body fat. It is also trusted by sportsmen to alleviate sore joints and tendons. Moreover, sportsmen who tend to experience sore shoulders, knees, and/or elbows while using Deca experience no pain and the associated pain is primarily due to intense workouts. However, the use of Deca Durabolin for a period of six to eight weeks can almost nullify this problem as the steroid can dramatically improve nitrogen retention and recuperation time between workouts.

Deca Durabolin Improves Immune FunctionIf that was not all, sportsmen who are regular or first-time users of anabolic steroids and worry about skin, scalp, and prostate complications can use this drug without second thoughts as Deca is converted to a less-potent compound by 5 alpha-reductase, the enzyme which converts testosterone to the more-potent DHT. In other words, this anabolic androgenic steroid gets somewhat deactivated in the prostate, skin, and scalp and all these tissues tend to experience an effectively-lower androgen level than other parts of the body that also means that hair loss, prostate complications, and skin problems are very rarely seen with the use of this steroid. In order to reap the optimum advantages of Deca, it is best used with testosterone. It is best used in moderate doses of 400 mg per week and the long life of this steroid makes it best suited to more traditional cycles and not the short alternating cycles.

Friday, February 7, 2014

COMING OFF ANABOLIC STEROID CYCLES

Sure, it’s easy to compile a drug stash, and if you can get past needle phobias, can successfully stack anabolic steroids, and suffer through the side effects of your cycle, you’re doing better than a lot of bodybuilders. But there’s one more hurdle for you to get over… how to come off of your cycle, relatively unscathed.


In the old days (the late 80’s and early 90’s), bodybuilders came off steroids much more often than they do today. A lot of that is because the number of appearances that bodybuilders made in the late 80’s, for instance, were far fewer than the number of appearances they make today. In fact, most pro bodybuilders are gone at least 2 weekends every month in between competitions. If they’re sponsored by or under contract with a major supplement company, they are often on the road far more than that. Because of the number of appearances these days, the pros—and many amateurs—need to remain in good condition, and that necessitates longer drug cycles. The fear that accompanies longer drug cycles is the catabolic phase—the one that will usher in muscle loss, fat gain, slower metabolism, etc.

In the late 80’s, I remember a friend of mine (a popular IFBB pro) who told me that he hadn’t gone off a drug cycle in well over a year. No breaks whatsoever! At that time, staying on a cycle for longer than 16-20 weeks was almost unheard of. So, I was inclined to believe it based on his hair-trigger temper, the quality of his physique (he had a perpetual “androgen sunburn”) and the odd hardness and mottled appearance he displayed.

I asked if staying on that long was messing with his head, and he proceeded to tell me that he had recently experienced suicidal feelings and tendencies. I asked, “Do you think there’s a correlation between being on steroids non-stop, and feeling suicidal, or at least, ‘pent up’?” He said he did, but that he was deathly afraid to go off of a cycle for fear he’d “lose size” and not be competitive enough in the current climate.  Today, that would be an even bigger concern, and the bells and whistles in this guy’s head would be deafening.

Don’t get me wrong, I’m not into telling pathetic cautionary tales, warning against the evils of ‘roids. My honest feeling is that most people can maintain a drug cycle for an extended period of time, and be healthy, if they know what they’re doing. It’s the coming off that is the hard part; whether over a short period of time or a long one. Naturally, coming off after 24 weeks is going to be harder than coming off after 10 weeks. 

Symptoms that follow going off an anabolic steroid cycle include: weight loss, muscle atrophy, loss of body strength, fatty deposits, as well as depression, lack of motivation and discipline and an actual aversion to the gym. In general, symptoms worsen when the individual has been on the cycle for an extended period of time. It’s the proportional kick in the ass!  The body gives back what you give it.

Drug Trade – Why We Make it More Difficult for Ourselves
Part of why people experience side effects in coming off a drug cycle is the fact that they haven’t planned for impending side effects while on the drugs. In other words, they start out planning for a 12 week cycle and choose drugs in combination that would suit that length of time. Once they decide to remain on a longer cycle, however, the game changes and the drugs they have been using during that 3 month cycle aren’t terribly conducive to the longer 18-20 week cycle. When they try to continue with the original drugs they’ve been taking, and extend the time alone, it becomes increasingly difficult to come off in any way that is correct or safe. In my experience, this is when bitch tits occur most often because people miscalculate the half-life of drugs and don’t take enough drugs to counteract aromatization, or to kickstart testosterone production. The latter provides a whole other set of side effects when facilitated improperly. 

Different Drugs…
Resuming testosterone production is the trickiest part of going off of any cycle, but particularly tricky following a long one. All steroids will cause a certain amount of lag in testosterone resumption, but among steroids some are worse than others. For instance, moderate testosterone suppressing drugs such as Primobolan, D-bol, Winstrol or Deca aren’t going to suppress testosterone production as much as hardcore drugs like Testosterone Propionate or Cypionate. However, testosterone suppression shoots up to about 30%-40% after just 10 days on a cycle. That doesn't mean that 100 days will put suppression into the negative zone, because it is not exponential. Testosterone suppression does level off at a certain point, but what happens is that the body’s own production of testosterone takes much longer to resume, the longer that body remains on a cycle. So, a male bodybuilder on a 10 week cycle, for instance, will have less time between cessation of the cycle and resumption of their own testosterone production than someone who stays on a cycle for 20 weeks. This is an important consideration because it dictates how much Clomid and HCG to take in order to get normal testosterone production back. 

Direct Relief
Clomid and HCG are the obvious choices to kickstart testosterone production again, but there are a host of other problems to tackle, too. Let’s first deal with this combination of drugs and then move on to some others that will help bridge the gap between your cycle and life off steroids. In order to re-start or increase the body's own testosterone production, doses of HCG are necessary. Essentially, what HCG does is directly and rapidly stimulate the testes’ Leydig’s cells. This is where testosterone production begins. But Clomid is also necessary because it completes the hypothalamohypophysial testicular axis. But Clomid therapy must begin prior to HCG therapy since it takes longer to become effective and has a great deal to do with half-life of steroids ingested over the period of time in question.
Roughly, this is approximately what a bodybuilder/ athlete should inject:

Administration of HCG: Middle of the last week of discontinuance of anabolic steroids
                                   5000i.u./ per day x 3 days (total: 3 days)
                                   5000i.u./every 5 days x 3 shots (total: 15 days)

The administration of Clomid is taken over the course of 2 weeks, and usually after HCG therapy begins:
                                   Two-50mg tablets/day x 7 days
                                   One-50mg tablet/ day x 7 days

Note: For those people who remain on cycles for longer than 12 weeks, I always recommend HCG injections that are a little more frequent in the last 15 days. I recommend 5 shots, in fact, rather than 3. I also recommend for everyone that they take additional steps to see that their exit from a cycle is a smooth and graceful one.

A Graceful Exit
Gracefully exiting a cycle in a general sense is listed above. But there is little information out there on other ways to bridge the gap between being full of anabolic steroids and being free of them. One thing you need to get over, however, before ever starting a cycle, is the notion that you can actually ameliorate symptoms by using natural means. Sure, these ergogenic aids can’t hurt you, but you’re going to be wasting money that you could be spending on legitimate non-steroidal chemical bridges, such as Cytadren, Clenbuterol and Cytomel.

Cytadren: It reduces cortisol levels exceedingly well just following the completion of a cycle. Typically, athletes will cycle it and gradually go from higher doses down to low doses in the hope to let the body’s production of cortisol trickle in slowly until the body becomes accustomed to it. Elevated cortisol levels are, of course, associated with a lot of undesirable symptoms, such as loss of strength, loss of muscle size, and fatty deposits. Typically, a 2-4 week cycle of Cytadren is common. Dose depends upon length of time on cycle, weight of athlete and other pharmaceuticals being used in conjunction.

Clenbuterol: This is also a successful cortisol blocker, and can and should be used in conjunction with Cytadren. Clenbuterol can also contribute to increases in strength gains or, in the case of a person just exiting a cycle, maintain current strength relatively well. Keeping fat stores at bay after stopping a cycle can also be an issue, but Clenbuterol can help athletes remain lean. Begin taking Clenbuterol about 1-2 weeks prior to cessation of the cycle, to overlap and ‘bridge’ the gap between the anabolic steroid cycle and the weeks that will be spent ‘resting’. Usually, I recommend people stay on Clenbuterol for about 8-10 weeks, including the overlapped time.

Cytomel: Many athletes take Cytomel in an effort to drop fat prior to a competition. This is a fairly serious investment in a potential future of obligatory intake of something for life. I do think it has its place after a cycle, however, because it can smooth rough edges of a metabolic rate that will inevitably dip below normal once the cycle has ended. I don’t advocate its use for women as much as for men, but if either feel the need to take it, take no more than 25-40mcg daily for no more than 30 days. Taper off by cutting pills in half until you are down to a few days of 12.5mcg at the end.

Thursday, January 23, 2014

High Testosterone

From magazine adds to TV commercials, with increasingly regularity you hear talk of those suffering from low testosterone. You’ve seen the commercials talking about “Low-T” and the treatment of the condition, but what about high testosterone, what about those suffering from high testosterone? Let’s be clear, if you’re a man with high testosterone you’re not suffering, in-fact, your quality of life is more than likely far greater than the man next to you. To understand this, we only need to understand two things, what testosterone is and what happens when our levels fall. Once we understand these two simple, very simple things, then we can have a grasp on what high testosterone can do for you.
Understanding Testosterone

Testosterone is the primary male hormone, the primary androgen, and by its nature is responsible for male sexual development and the male characteristics. While testosterone is the primary male hormone it is also produced by women, although in far lesser amounts. In either case, with men and women testosterone is essential to our health and function; men simply require more, about ten times the amount. By design, testosterone affects both our physical and mental state, as well as our overall sexual function.
Low Testosterone

Millions upon millions of men worldwide suffer from low testosterone; in the U.S. alone it is estimated to be between 15-20 million. Many women suffer from testosterone related issues too; women who are on birth control often find their levels suppressed, and post-menopausal women often find they have a problem. Even so, it will be men who carry the brunt of the weight and when levels fall rest assured it is no fun for anyone. Low testosterone can cause many unwanted symptoms, including but not limited to:

Loss of Libido

Erectile Dysfunction

Loss of Muscle Mass

Loss of Strength

Depression

Increased Body-Fat

Inability to Lose Body-Fat

Loss of Focus

Loss of Energy

Insomnia

Lethargy
The Reverse

When we have high testosterone levels, we can take the list above and completely flip it around. When we have high testosterone levels, not only will the above symptoms never occur, but regarding each one that area of our life will be improved upon. No, this does not automatically mean those with high testosterone will be behemoths of muscle and strength, training and diet will still dictate this end. However, men with high testosterone will be in better shape, enjoy a higher quality of life and simply possess a better sense of well-being. Men with high levels can expect the following:

Increased Muscle Mass

Increased Strength

Decreased Body-Fat

Increased Clarity of Thought

Increased Energy

Enhanced Mood

Increased Libido

Better Rest

Increased Rate of Recovery

Obtaining High Levels

There is no set in stone normal testosterone level. As individuals, we all produce varying amounts of the hormone, and the amounts naturally produced can vary dramatically from person to person. In any case, in most therapeutic circles a total testosterone reading of 300ng/dl or below is considered low with anywhere from 500ng/dl-700ng/dl being considered adequate. As you can see, that’s quite a variation.

In any case, we can describe high testosterone as any amount above your baseline average, and to obtain it there is only one true way; anabolic steroids. If you desire high testosterone levels you will need to supplement with the primary anabolic steroid testosterone. If you need more gas in your car then guess what, you need to put gas in the car, and if you want more testosterone in the body you’re going to have to give the body testosterone. There are certain foods you can eat that will naturally stimulate production and there are a few testosterone boosting supplements, but to obtain true high levels, pure exogenous testosterone is the only way.

Wednesday, January 8, 2014

Anabolic steroids making musclemen infertile

Bodybuilders destroying their chance of becoming fathers in their quest to bulk up, specialists report.



Growing numbers of men are becoming infertile because they take anabolic steroids in their quest for a muscular body, doctors have warned.

Urologists are seeing more and more men whose difficulty in becoming a father is linked to consumption of the muscle-boosting drugs.

Steve Payne, a consultant urologist at the Manchester Royal Infirmary and a council member of the British Association of Urological Surgeons, said: "Many fit young men who believe they are at the peak of physical perfection don't believe it could be their fault when their wives or girlfriends find it difficult to become pregnant.

"They are insulted when it is suggested that they undergo a sperm test, and horrified when the results of those tests show an absence of sperm in the sample."

Such men are then referred to a urologist, and undergo a blood test. If they have been using steroids, they often have what Payne calls deranged levels of sex hormones.

Men who regularly go to the gym should avoid taking steroids to bulk up, Payne added.

Acne, aggression and an unexplained, orangey skin tone akin to a tan are also associated with use of steroids.

Dr Allan Pacey, a senior lecturer in andrology at Sheffield University, warned: "It is a very real risk that men who take anabolic steroids will become infertile. It's almost certain that they [the steroids] will have an effect of some sort on their fertility and, in the worst-case scenario, that sperm production will stop altogether.

"These patients walk through the door looking like Arnold Schwarzenegger in his younger days. They are having fertility problems, and it suddenly becomes obvious where the problem may lie."

Some men who stop taking steroids never regain their reproductive capacity and for others it takes years for normal sperm production to resume, Pacey added.

Friday, December 27, 2013

Boost Your Anabolic Hormone Levels

Anabolic steroids use appears to be on the rise. With the great increase in modern recombinant DNA technology, steroids such as growth hormone, growth factors and testosterone-based analogs have become increasingly more available and affordable. Despite their renewed popularity however, anabolic steroids are illegal and have negative effects on health, reproductive status and even personality. In response, this article aims to provide some basic information on anabolic steroids and how to boost the body's own production levels naturally, using exercise.

What is an anabolic hormone?

The definition of anabolic is "to build up"- therefore anabolic steroids are hormones that cause increases body and muscle size. Actually, not all "anabolic steroids" are steroids but they are all hormones. An example of an anabolic steroid hormone is testosterone and its analogs. An example of an anabolic polypeptide/non-steroid hormone is growth hormone. Basically, hormones are chemical messengers released from certain tissues into the blood in response to a stimulus. Their role is essentially to help the human body adapt and remain in a state of balance or "homeostasis". While the body is quite efficient at regulating its anabolic state on its own - the temptation exists to use large quantities of anabolic hormones to magnify the results. As recently as 15-20 years ago, growth hormone had to be extracted form the pituitary glands of cadavers. Now however, modern science is able to manipulate the DNA of bacteria to produce large quantities of the hormone. Steroid use has always been rife in bodybuilding arena, but with peer pressure and ever-increasing expectations of sport performance, anabolic steroid use has become commonplace in sports too - even among high school age athletes.

How do I boost my levels of testosterone and growth hormone?

It is possible to increase anabolic hormone production naturally however - the simplest method of doing this is by regulating the intensity of the weightlifting session. This is achieved by manipulating volume (sets and reps), load (%1RM*) and rest periods. Evidence indicates that exercises that recruit large muscle groups (legs and back) in exercises such as squats and deadlifts and that are performed with high intensity and moderate volume boost serum testosterone concentrations. Therefore the exerciser should use heavy loads (85-95% 1 RM) and multiple sets/exercises separated by short rest periods (30 -60s). Testosterone, the male sex hormone is responsible for the increased muscle mass and strength observed in men. This steroid hormone operates both on a gene level to increase muscle protein production (increased gene transcription). It is also suspected to work on the central nervous system, allowing greater muscle activation by motor neurons, resulting in greater force production. (It is unlikely that herbal testosterone "precursors" such as tribulus terestris have a large impact on production - the exerciser should save his time and money and devote more effort into sensible eating and exercising according to these guidelines.)

Human growth hormone (HGH) is a polypeptide (non steroid) hormone released form the pituitary gland at the base of the brain, and its release similar to testosterone, is dependent on the level of "stress" experienced by the body. Its main functions are to increase the transport of amino acids over cell membranes and to increase the synthesis of muscle protein, connective tissue (e.g. collagen) bone and cartilage thus directly causing "growth". It also is responsible for increasing the level of glucose and fatty acids in the blood, and therefore has a direct body-fat reducing quality. Studies involving the release of growth hormone during exercise indicate that a typical bodybuilding program of multiple sets (higher volumes) of moderate intensity (e.g. 10RM) separated by short (1 min.) rest periods produce the largest increases. Many of the actions of growth hormone are actually mediated by another hormone called IGF-1 (insulin-like growth factor-1) released by the liver and other organs in response to HGH. The release of this powerful stimulator of muscle growth has been shown to increase in response to the consumption of a carbohydrate and protein supplement before and immediately after a weightlifting workout.

In conclusion, it is hoped that this article has demonstrated that there are alternatives to using illegal and health threatening anabolic steroids. The human body is a marvel at adapting to stresses such as exercise and weightlifting without the need for external hormone administration. This article has highlighted that is in fact possible to manipulate the body's own natural production of the same substances simply by regulating the intensity of the weightlifting session.

*1RM = the maximum amount of weight that can be lifted with good form for a single repetition.

Wednesday, November 20, 2013

Can Using Steroids Make Your Penis Shrink, Make Your Penis Grow, Or Will Your Penis Stay The Same Size?

A lot of guys ask this question before they use illegal steroids or legal steroids for the first time. The quick and easy answer is this: if you are over the age 21 and no longer in your natural growth cycle then NO, steroids will not make your penis grow. If you are under 21 and are still in the natural growth cycle then the answer is YES steroids can impact penis growth. This is one of the reasons why basically everyone will tell you that you should NEVER use anabolic steroids of any kind unless you are 21 years of age or older. Take anabolic steroids at a younger age can have a variety of effects many of which would be undesirable for most though some would be considerable desirable by most.

The science behind steroids on penis growth in the simplest terms goes like this, people who use Anabolic Steroids have to basic classes that they breakdown all steroids into; dry compounds and wet compounds. “Dry” steroidal compounds are the ones that do not convert to estrogen and the “wet” steroidal compounds are the ones that do convert and/or behave like estrogen in the body. There is no perfected science or understanding yet in the world of steroids but as far as we understand it if you are young enough and still growing, the use of dry steroids should increase the size of your penis, how tall your grow, etc. Conversely, the use of wet steroids should decrease the size of your penis, how tall you will grow, etc.

So to recap so far, if you are fewer than 21 years of age, we never suggest the use of steroids. Instead there is a proven supplement with loads of research behind it that safely and naturally shift your androgen levels towards a higher levels of DHT, which hypothetically could increase your penis size, height, etc. Any guesses? Start with the letter C…….that’s right, Creatine! Demonstrated safe, time and again for use from teens all the way to the very elderly creatine truly is a staple supplement that should be used by most everyone!
Steroids And Penis Size For Those Over 21? Will It Help? The Answer is…

No. This is a MYTH. You’re penis will not shrink or grow if you are over 21 and using steroids. This newer urban myth that steroids will make your penis shrivel up to the size of a raisin is because of the long known effect that steroids has on the testicles. FACT: When use steroids you’re balls do shrink up some. This testicular shrinkage is attributed to the natural “shut down” that happens in the body when steroids from the outside coming signal the body that they testies don’t need to keep making testosterone internally as normal. This shrinkage effect reverses in 1-2 months after a cycle or you can use PCT, Post Cycle Therapy, to speed up this recovery time when your body begins to make its own testosterone again.

Thursday, October 3, 2013

Anabolic Steroids and Fertility

There are a number of side effects users will experience when taking Anabolic Steroids. Some are short term and others may have long term side effects. Unfortunately any side effects will in most cases also effect the male fertility health. Some of these side effects can include:

Short term effects

    Puffiness and swelling in the face and neck due to increased water retention.
    Development of breast tissue in males.
    Increased risk of injury to muscles and joints.
    Increase in muscle mass.
    Heightened aggression, sleeping disorders, anxiety and irritability.
    Stunted growth if taken during adolescent growth spurts due to skeletal maturation and accelerated puberty changes.
    

Long term effects

    Growth of breasts due to the high level of testosterone some of which the body converts to oestrogen.
    Increased erectile dysfunction and shrinking testicles.
    Heart and liver disease - some steroids are toxic to the liver.
     Kidney disease due to the increase in toxins to be broken down.
    Aggressive behaviour and depression.
    Jaundice from high levels of steroids - affects liver function.
    Increased blood pressure.
    Prostate enlargement.


Anabolic Steroids and male infertility are often linked due to the effects on the body as mentioned here.  Any increased toxins in the body have the potential to affect the sperm being produced.

A semen analysis will give a good indication of the health of the sperm if a male has used steroids previously and is now having difficulty with infertility. A low sperm count will also be detected by going for a semen analysis.

Fortunately medical technology and advancement in procedures such as sperm washing as well as ICSI - Intra-Cytoplasmic Sperm Injection could assist men whose fertility may have been affected by the usage of Steroids.

Your doctor will be able to advise you on using an Assisted Reproductive Technology (ART) procedure in the event of being diagnosed with infertility due to this usage.

Natural remedies for infertility

In order to get rid of the toxins and increase your health status and hormonal balance, changing your infertility diet and considering the alkaline diet may assist in correcting your sperm problems.

Many of the side effects mentioned can be corrected by immediately stopping the usage of these substances, as well as considering lifestyle changes and partaking in moderate exercise such as walking and swimming or yoga.

Friday, September 27, 2013

Gynaecomastia causes and problems.

Gynaecomastia (often referred to as ‘man boobs’) is the enlargement of male breast tissue. Gynaecomastia appears as a rubbery or firm mass that starts from underneath the nipple and then spreads outwards over the breast area. The tissue is enlargement of glandular tissue, not fat tissue. In about half of cases, enlargement is found in both breasts; in the other cases it only affects one breast.

Gynaecomastia can happen in males of any age or weight. Obese men can appear to have man boobs as they have fat tissue all over the body including the breasts; this is not true gynaecomastia.

The growth of breast tissue can be painful or tender. This should always be checked by a doctor. Gynaecomastia can appear as a small lump that becomes tender as the mass becomes larger.
How common is gynaecomastia?

Gynaecomastia is very common in boys going through puberty, happening in more than half of all normal adolescent males, and usually goes away over time. In older men, enlargement of the breast tissue happens in about one-third of men.
What causes gynaecomastia?

Gynaecomastia commonly appears during infancy, puberty and older age. All males have the male sex hormone testosterone as well as low levels of the female hormone oestrogen, which controls breast tissue growth. When the testosterone to oestrogen ratio changes (that is, there is an imbalance in the levels of these two hormones with relatively higher amounts of oestrogen), breast tissue can grow.

Some men with gynaecomastia have higher than normal oestrogen levels.

Many newborn male babies have enlarged breast tissue because of transfer of oestrogen from the mother during pregnancy. The oestrogen goes down after birth so this type of gynaecomastia is temporary.

During mid to late puberty more oestrogen than testosterone is made by the maturing testis until the time when the testes start to make testosterone at adult levels. Gynaecomastia starting during puberty often goes away, but in less than one in 20 adolescent boys it continues into adulthood.

As men get older there is often a gradual decrease in testosterone levels (and therefore the ratio of oestrogen relative to testosterone goes up) and this can lead to gynaecomastia.

Gynaecomastia can also be caused by genetic problems, chronic diseases (especially kidney and liver disease) or some medicines. Men who take anabolic steroids for sporting performance or body building often develop gynaecomastia. In rare cases, gynaecomastia can be caused by a tumour in the testis or adrenal glands that makes large amounts of oestrogen.
What genetic problems cause gynaecomastia?

Klinefelter’s syndrome (KS), a chromosomal problem that affects one in every 650 males, is the main genetic cause of gynaecomastia. Men with KS have an extra X chromosome and do not make enough testosterone for the body to function normally. Male physical and reproductive development is affected and men with KS have small testes, are almost always infertile and often develop gynaecomastia.

Men with KS have an imbalance in their oestrogen to testosterone ratio because they have low testosterone levels. Testosterone therapy brings the ratio back to normal and helps prevent (when started at puberty) or improve the gynaecomastia, but it may not completely fix it and plastic surgery may be needed.
How can medicines or drugs cause gynaecomastia?

Medicines that can cause breast growth in men include certain antidepressants, medicines used for high blood pressure and tuberculosis, and some chemotherapy agents. Antibiotics, anti-ulcer and cardiovascular medicines have sometimes been found to change the balance of hormones in the body.

Drug abuse, especially the use of anabolic steroids, but also marijuana, opioids and excessive alcohol intake (that has caused chronic liver disease) can cause gynaecomastia.

Medicines that block the effects of testosterone are used in the treatment of prostate cancer and can lead to gynaecomastia.

In rare cases, the partners of women using topical oestrogen cream or gel for hormone replacement therapy may absorb enough oestrogen through regular, prolonged contact to cause gynaecomastia.

Thursday, September 12, 2013

Anabolic Steroid Abuse

Anabolic steroids are substances similar to the male hormone testosterone. They are used to promote masculine features, increase growth, build muscle tissue, and strengthen bones. Common anabolic steroid medicines include fluoxymesterone and nandrolone. All anabolic steroids available in the United States require a prescription and are used to treat conditions that occur when the body produces abnormally low amounts of testosterone, such as delayed puberty and some types of impotence.

Some people take legal dietary supplements that have certain steroid hormones also made by the human body. One such drug is dehydroepiandrosterone (DHEA). The body can turn DHEA into other steroid hormones, including testosterone, estrogen, and cortisol. People use it to try to make their muscles bigger. Whether such products actually work has not been proved. But if you take them in large amounts, they can cause the same side effects as anabolic steroids.

When anabolic steroids are taken without a medical reason, it is usually to improve performance in sports or to increase muscle size and reduce body fat. Some teens abuse steroids along with other drugs.

When these medicines are taken to supplement physical development, the dose is 10 to 100 times higher than when they are taken for medical conditions. They may be taken as a pill, an injection into a muscle, or a gel or cream rubbed on the skin. Often more than one of these drugs is used at the same time (stacking), or the drug is taken in a cycle from no drug to a high dose over a period of weeks to months (pyramiding).

Anabolic steroid use can cause a wide range of side effects affecting many systems in the body. Some of these effects can be permanent. Systems affected include the:

    Hormonal system. In men, anabolic steroids reduce sperm count, shrink testicles, cause male-pattern balding, and enlarge breasts. In women, they cause masculine effects, such as decreased breast size and body fat, enlarged clitoris, and a deeper voice.
    Musculoskeletal system (muscles and bones). A teen who abuses anabolic steroids may not reach his or her full adult height, because these drugs can stop bone growth before it is complete.
    Cardiovascular system (heart and blood vessels). Some anabolic steroids affect the level of fat (lipids) in the blood and may cause a heart attack or stroke, even in a very young person. Anabolic steroids also increase blood pressure.
    Liver. Anabolic steroids can cause liver cancer.
    Skin. Anabolic steroids cause oily skin and acne. Skin infections can occur if the person injects steroids. And an infection can become severe if the drug was contaminated with a virus or bacteria during its preparation.
    Brain. Anabolic steroids may cause irritability, homicidal rage, uncontrollable activity level (mania), or false beliefs (delusions).

Tuesday, July 16, 2013

Effect of anabolic steroids on sexual desire. Studying the effects and therapy.

Sexual desire (or libido) is mainly controlled by testosterone. Anabolic steroids can lead to an increase in libido. Increased libido may be a problem, because the use of androgens in high doses may also increase the likelihood of violence.

The more common problem is the state after the use of anabolic steroids as testosterone production in the body usually stops around for a few months. The concentration of testosterone in the blood stream is not sufficient to maintain a normal libido, so these hormonal disorders can cause loss of libido.

Very marked reduction in the concentration of testosterone can also lead to erectile disorders. In particular, the simultaneous development of data breaches weightlifting sports performance can deteriorate significantly, in connection with what is often a serious need for the re-use of anabolic steroids.

Studying the effects and therapy

Anabolic-androgenic steroids are likely to disrupt the normal function of the pituitary gland. A similar effect occurs in women who take contraceptive preparations. People who use anabolic steroids are very naslysheny on emerging issues, and some of them are turning to doctors.

According to the medical examination, the other obvious violations are usually absent, and patients can look like healthy people. There may be side effects associated with the use of androgens (e.g., acne, skin stretching portions, breast enlargement and possible traces of injections). As a result of prolonged use of androgens may experience a pronounced reduction in the size of the testicles.

Effect of anabolic androgenic steroids on reproductive function is largely dependent on the use of drugs, doses and timing of application. According to the hormonal studies, reflecting the testicular function, there may be typical violations. According to studies of seminal fluid, a significant proportion of patients may experience a complete absence of sperm. Other people violation can be expressed to a lesser extent.

The changes caused by the use of anabolic-androgenic steroids are reversible, but to restore normal sperm production can take a year. In most cases, the most effective and efficient method is to stop the use of anabolic androgenic steroids. A prerequisite for successful therapy is to understand the relationship between the person actually use and development of androgen disorders, as well as the realization that the recovery will take time.  Of great importance is to motivate patients.

Maintaining physiological concentrations of testosterone (ie, testosterone replacement therapy) may be required in the recovery phase, when there is heavy and prolonged hypothyroidism. However, there is a risk of abuse. Replacement therapy leads to a longer period of sperm production.

The use of anabolic androgenic steroids is not the only cause of male infertility. If the violation is apparently not related to the use of anabolic androgenic steroids or not marked recovery after cessation of anabolic-androgenic steroids, it is necessary to search for other causes of violations of sperm production.