GLVitamins

Thursday, April 17, 2014

Anabolic Steroids and Infertility

Anabolic Steroids are synthetic substances similar to the male sex hormone testosterone. If used consistently from a young age they can be detrimental to the users health because they upset the body's hormonal balance.

Anabolic Steroids are known to have a variety of harmful side effects, are out of bounds for athletes and users are required to only take them under prescription of a medical doctor. Yet many people take them for the short term benefits they provide - for athletes to improve performance or to enhance physical appearance.

These drugs are often sold on the black market and because their short term benefits are so attractive users tend to ignore the dangerous and possible long term side effects. Users do not consider the effects these substances may have on their fertility health.
   

 Medical Benefits

Steroids aren't only used for bulking up but can be prescribed for legitimate medical reasons. Your medical practioner is well aware of the side effects and will prescribe a dosage with this in mind to cater for your particular situation.


 Some of the medical uses are:

    Men with too little testosterone - Whether it's due to an accident or a disease; such as testicular cancer, some men have to have their testicles removed.Their bodies will no longer be able to produce testosterone. They will be given prescribed oral anabolic steroids to replace the testosterone.

    People with chronic illnesses, such as cancer or even AIDS can use anabolic steroids to stimulate their appetite and help build muscle.
    Pituitary problems -  Steroids can help adolescent males with pituitary problems. When the pituitary gland malfunctions, the brain signals to the testes may not function correctly and the testes therefore does not produce testosterone. Boys suffering from this condition can be prescribed steroids at the appropriate age, as per his doctor. This treatment will allow them to develop secondary sexual characteristics, such as a deepening of the voice, growth spurts and pubic and facial hair.

Anabolic Steroids and fertility

There are a number of side effects users will experience when taking these substances. Some are short term and others may have long term side effects. Unfortunately any side effects will in most cases also effect the male fertility health. Some of these side effects can include:

Short term effects

    Puffiness and swelling in the face and neck due to increased water retention.
    Development of breast tissue in males.
    Increased risk of injury to muscles and joints.
    Increase in muscle mass.
    Heightened aggression, sleeping disorders, anxiety and irritability.
    Stunted growth if taken during adolescent growth spurts due to skeletal maturation and accelerated puberty changes.
    

Long term effects

    Growth of breasts due to the high level of testosterone some of which the body converts to oestrogen.
    Increased erectile dysfunction and shrinking testicles.
    Heart and liver disease - some steroids are toxic to the liver.
    Kidney disease due to the increase in toxins to be broken down.
    Aggressive behaviour and depression.
    Jaundice from high levels of steroids - affects liver function.
    Increased blood pressure.
    Prostate enlargement.


Anabolic Steroids and male infertility are often linked due to the effects on the body as mentioned here.  Any increased toxins in the body have the potential to affect the sperm being produced.

A semen analysis will give a good indication of the health of the sperm if a male has used steroids previously and is now having difficulty with infertility. A low sperm count will also be detected by going for a semen analysis.

Fortunately medical technology and advancement in procedures such as sperm washing as well as ICSI - Intra-Cytoplasmic Sperm Injection could assist men whose fertility may have been affected by the usage of Steroids.

Your doctor will be able to advise you on using an Assisted Reproductive Technology (ART) procedure in the event of being diagnosed with infertility due to this usage.

Tuesday, April 1, 2014

HMG: The Miracle Fertility Med?

When we administer certain hormones into our bodies, various cells and organs have the ability to sense this. Your body 'sees' this increase in testosterone or similar molecules and as a result it can sense that it is in a higher concentration than what would be normal in the blood. As a result, it will shut down its own testosterone production. There are various mechanisms involved in this, but an important one is the cessation in production of luteinizing hormone (LH) and follicle stimulating hormone (FSH), produced by the pituitary gland. These hormones are required for the testes to be stimulated to produce testosterone but also play a role in sperm production.

From a blood-testosterone aspect this all seems okay to us, sure we have shut down natural testosterone production, but we still have testosterone in us; right? Well, one of the big problems with regards to fertility is that the testes do not work like that. The Leydig cells in the testes produce testosterone when stimulated by LH. Testosterone is released from these cells which are in close proximity to the Sertoli cells. When Sertoli cells see a high concentration of testosterone, they are stimulated to produce and mature sperm by the process of spermatogenesis. A high blood concentration of testosterone will not do this job. Thus administering anabolic androgenic steroids (AAS) will shut down natural testosterone production which will in turn slow down (and eventually near turn off) the proper formation and maturation of sperm. Thus infertility is a serious issue with use of anabolic steroids.

Classically, HCG has been seen to rectify this problem in males. HCG is an LH analogue – it 'looks' like LH to the body and so it can stimulate the Leydig cells to produce testosterone and in turn, hopefully, restore fertility. In some cases this will occur, and many people have had success from HCG therapy relating to infertility. However, the response is not robust and certainly with longer shut-down periods, many often find the use of HCG (even in combination with other post cycle therapy (PCT) medicines such as clomifene (aka clomid) and tamoxifen (aka nolvadex), etc) to not be effective at restoring fertility.

Furthermore, what HCG lacks is to produce the important effects that FSH inflicts upon fertility. FSH, despite its name, is important in male fertility in two main pathways. The first thing it does is to enhance the action of LH, by increasing the amount of protein that will 'see' testosterone in the Sertoli cells. The more easily these cells can see testosterone, the more likely spermatogenesis will occur. Secondly, FSH enhances the maturation of sperm by effects on their primary division. These are two important aspects of the role of FSH in the male testes that HCG is not optimal in promoting.

HMG, or its full name Human Menopausal Gonadotropin, bears similarities to HCG in that while HCG is similar to human LH, HMG contains actual LH. Additionally (and crucially) though, HMG also contains purified FSH. The combination of these two hormones perform the effects described above: induction of natural testosterone production by Leydig cells, and subsequent formation and maturation of sperm cells. The result is improved and potentially recovered fertility for the male concerned.

Does HMG really work?
So often we hear about various different drugs and the science for them is sound, but real world evidence is lacking. There are a few studies performed on HMG over the last 25 years, and I would like to draw your attention to two of these studies, pointing out a few key details. The first goes back to 1985 by Ley & Leonard and is an important study as it looks at males who had previously encountered anabolic steroids treatment (treatment for low hormone levels including mainly testosterone). This study is available online and I encourage you to read it in more detail than the brief summary I will provide here.

They looked at 13 hypogonadotropic men all of who had undetectable levels of LH/FSH, lower than normal levels of testosterone and azoospermia, thus were unable to currently conceive. Obviously with the low hormonal levels there were issues with libido as well. Furthermore, there were instances where upon testis biopsies, Leydig cells were completely absent. Despite this, all 13 men responded to treatment with HCG with increasing testosterone levels. However, upon addition of HMG treatment, most men saw a further increase in testosterone, sometimes very large. HCG was able to increase sperm counts in most men slightly; however, only upon addition of HMG were sperm counts above 'normal' fertility levels (i.e. 20 million per ml) observed. The study indicates that the addition of HMG therapy surpasses any level that HCG treatment could achieve alone. Admittedly this is a particular subset of men who have medical conditions and abnormal hormone issues, but the results are interesting nonetheless.

The second is more recent by Buchter et al in 1998. This is even more interesting from the point of view that it looks at three times the number of cases as the previous study and in a different manner. Again, this study can be found online and I encourage you to read it. The most interesting result you could take away from this study is that in the group of men treated who suffered from hypopituitarism, all 21 treated with HCG/HMG achieved spermatogenesis and a large proportion (81%) was able to successfully achieve pregnancies. The discussion of this article is most interesting as it raises the points from its own study and the literature that many in the field believe that to achieve spermatogenesis and pregnancy in a gonadotropin-compromised individual requires combinational therapy of HCG and HMG. The important point to note is that HCG is not sufficient alone in many cases.

Given the fact that other studies point to HMG increasing endogenous testosterone further than HCG can, as those who have relatively 'normal' pituitaries but have compromised their function due to AAS use, it would be wise to consider the use of HMG. This would not only be for purposes of fertility, but to induce natural testosterone levels back to normal values when they have been suppressed. Treatment in this latest study was the use of HCG twice per week at 1000-2500IU per dose (Mon-Fri) and HMG three times per week at 75-150IU (Mon-Wed-Fri). Thus for bodybuilders seeking to regain fertility, spermatogenesis and restore natural testosterone levels but wishing to keep costs down, a weekly dose of the lower ends should be employed for at least one month.

A schedule would involve:
Monday: 1000-1500IU HCG + 75IU HMG
Wednesday: 75IU HMG
Friday: 1000-1500IU HCG + 75IU HMG

Depending on the amount of suppression this cycle may need to be lengthened for a further period.

Tuesday, March 18, 2014

Melanotan in Bodybuilding

To get a high quality bodybuilding competition tan athletes need to use the correct tanning products. The right color tan applied in the right way plays an important role between winning and losing a bodybuilding competition. A poor tan can seriously affect your chances of winning, whereas getting the very best ultimate tan can seriously improve your chances of success. So if you are serious about your On Stage Look then you should be very carefully while choosing method of tanning.

Now a beautiful and lasting tan may be obtained without UV exposure or fake tan. Tanning process in the body is the production of pigment in the skin cells called melanin. Melanin is produced by melanocytes, which are located in the basal layer of the epidermis. The stimulation of melanocytes to produce melanin is done by melanocortin hormone. Melanin absorbs harmful UV radiation, transforming them into harmless heat through a process called “ultrafast internal conversion.” By this process, the melanin can reduces the generation of free radicals to a minimum, and so prevents indirect DNA damage which can produce malignant skin melanomas.

Melanotan represent a hormone, analogue of melanocyte-stimulating (a-MSH) human hormone by which the body produces melanin that as we said earlier is protective pigment that protects the skin from harmful UV sun exposure. Melanotan hormone or simply said melanotan has additional properties – significantly increases the sex drive, reduces appetite, causing a persistent aversion to food, due to what can be achieved a powerful weight loss.

Melanotan was first synthesized at the University of Arizona. Researchers knew that the best way to protect skin against cancer is the activity of melanin in the cells, that is, the process of tanning. They suggested that the most effective way to protect skin against cancer will be stimulation of natural pigmentation system to produce a protective tan before exposure of skin to UV radiation.

In May 2010 the Italian Medicines Agency (AIFA – Agenzia Italiana del Farmaco) became the first national organization in the field of health, approving Melanotan as therapeutic agent for Italian citizens, reducing sensitivity to sunlight. In other countries it is widely used under the personal responsibility.
Melanotan is available both injectable stuff and nasal spray. (to see instruction please click here) After reaching the desired hue tanning frequency of use can be reduced.
Remember – the more you expose your skin to UV-radiation (solarium, sun) when taking Melanotan, the deeper and darker your tan will be (Melanotan stimulates human body to produce melanin, and thus, the skin darkens in response to UV-radiation instead of burning).
Then let’s make a summery, Melanotan apply:
- To obtain a stable effect of bright and beautiful tan without resorting to extended contact with sunlight or fake tan;
- In order to obtain improved contrast tan using additional exposure to the sun or solarium;
- In the case of interdiction to bronze or attend solarium, in order to protect against skin cancer and sunburn, especially in areas exposed to permanent effects of the sun;
- Melanotan is used to activate the sexual function and stabilizate libido;
- Also Melanotan is prescribed in cases of uncontrolled food intake, to significantly reduce appetite.
In some cases the usage of Melanotan can cause nausea, flushing of the face, decreased appetite, tiredness. Not everyone gets these side effects, but if it occurs it’s usually only after the first few dosages until the body adapts.

Thursday, March 6, 2014

Anabolic Steroids and Muscles

Anabolic steroids, known technically as anabolic-androgen steroids or colloquially as "steroids" (or even "roids"), are drugs that mimic the effects of testosterone and dihydrotestosterone in the body. They increase protein synthesis within cells, which results in the buildup of cellular tissue (anabolism), especially in muscles. Anabolic steroids also have androgenic and masculinity-enhancing properties, including the development and maintenance of masculine characteristics such as the growth of the vocal cords, testicles and body hair (secondary sexual characteristics). Anabolic-androgenic steroids were first isolated, identified and synthesized in the 1930's, and are now used therapeutically in medicine to induce bone growth, stimulate appetite, induce male puberty and treat chronic wasting conditions, such as cancer and AIDS. Anabolic steroids also increase muscle mass and physical strength, and are therefore used by athletes and bodybuilders alike to enhance strength or physique. Known side effects include harmful changes in cholesterol levels (increased Low density lipoprotein and decreased High density lipoprotein), acne, high blood pressure and liver damage. Some of these effects can be mitigated by taking supplemental drugs.
Mechanism of action

The pharmacodynamics of anabolic steroids are unlike peptide hormones. Water-soluble peptide hormones cannot penetrate the fatty cell membrane, and only indirectly affect the nucleus of target cells through their interaction with the cell’s surface receptors. However, as fat-soluble hormones, anabolic steroids are membrane-permeable, and influence the nucleus of cells by direct action. The pharmacodynamic action of anabolic steroids begins when the exogenous hormone penetrates the membrane of the target cell and binds to an androgen receptor located in the cytoplasm of that cell. From there, the compound hormone-receptor diffuses into the nucleus, where it either alters the expression of genes or activates processes that send signals to other parts of the cell. Different types of anabolic steroids bind to the androgen receptor with different affinities, depending on their chemical structure. Some anabolic steroids such as methandrostenolone bind weakly to this receptor in vitro, but still exhibit androgenic effects in vivo. The reason for this discrepancy is not known. The effect of anabolic steroids on muscle mass is caused in at least two ways: first, they increase the production of proteins; second, they reduce recovery time by blocking the effects of the stress hormone cortisol on muscle tissue, so that catabolism of muscle is greatly reduced. Some hypothesize that this reduction in muscle breakdown may occur by way of anabolic steroids inhibiting the action of other steroid hormones called glucocorticoids, which promote the breakdown of muscles. Anabolic steroids also affect the number of cells that develop into fat-storage cells by instead favoring cellular differentiation into muscle cells. Additionally, anabolic steroids can decrease fat by increasing basal metabolic rate (BMR), since an increase in muscle mass increases BMR.
Physical effects

Anabolic steroids are testosterone and dihydrotestosterone hormone mimics that stimulate anabolism, specifically protein synthesis and muscle hypertrophy. Due to its similarity to the male sex hormones, using anabolic steroids can result in masculinization of women and changes to secondary sex characteristics of men. This makes steroids attractive to those wishing to alter their appearance, particularly for body building. Further negative side effects of anabolic steroids include stunted growth in adolescents, increase in cholesterol levels, high blood pressure, acne, liver damage and changes to the left ventricle of the heart, not to mention potential psychiatric issues. Despite these side effects, anabolic steroids can be used therapeutically to stimulate bone growth and appetite, and treat chronic wasting conditions associated with cancer and AIDS, though at much lower dosages than those used for performance enhancement.
Steroid abuse

Abuse of anabolic steroids differs from the abuse of other illicit substances, because the initial use of anabolic steroids is motivated not by the immediate euphoria that accompanies other abused drugs such as cocaine, heroin and marijuana, but by the user's desire to change their appearance and performance, characteristics of great importance to adolescents. These effects can boost confidence and strength, leading the user to overlook the potential serious long-term damage that these substances can cause. Due to the unfair advantage given to athletes and competitors who use anabolic steroids, all major sports associations have banned their use.

While anabolic steroids can enhance certain types of performance or appearance, they are dangerous drugs, and when used inappropriately, they can cause a host of severe, long-lasting and often irreversible negative health consequences. For example, they can stunt the height of growing adolescents, masculinize women and alter sex characteristics of men. Anabolic steroids can also lead to premature heart attacks, strokes, liver tumors, kidney failure and serious psychiatric problems. In addition, because steroids are often injected, users risk contracting or transmitting HIV or hepatitis.

Tuesday, February 18, 2014

Deca Durabolin Improves Immune Function

Deca Durabolin, which is also known as Deca and Nandrolone decanoate, is a popular anabolic steroid that is commonly recommended to provide dramatic relief to HIV/AIDS patients and use of this steroid is associated with immune system enhancements. Belonging to the category of anabolic-androgenic steroids and classified as a 2.16 anabolic steroid, it has the ability of stimulating endurance and muscle function gains and promoting muscle growth and size to a significant extent.

It is also beneficial to mask minor joint pain and old nagging injuries and for reducing the inflammation of soft tissues; Deca is also used for the development and maintenance of masculine (secondary sexual) characteristics, including growth of the vocal cords, testicles, and body hair.

Deca Durabolin Improves Immune Function

One of the biggest benefits why Deca Durabolin is extremely popular with sportsmen and fitness conscious people, especially those looking for immune function improvements, is that it improves cell-mediated immune response and improves the activity of macrophages besides reducing the incidence of post-operative infection. It is equally effective in improving immune function, like increasing CD8+ (Cytotoxic cells with CD8 surface protein) count that is highly correlative with improved survival in HIV.

In addition to this, the use of this anabolic steroid is characterized by significant anabolic effects and minimal androgenic side effects. The fact that the side effects of other steroids and performance enhancing drugs like gynecomastia and problems with liver enzymes, blood pressure, or cholesterol levels are rarely seen with the use of this drug means that it is best for even those who are prone to such side effects.

Deca is commonly stacked with Dianabol, Anadrol, and Sustanon and is best known for its abilities to promote good muscle size and strength gains while reducing body fat. It is also trusted by sportsmen to alleviate sore joints and tendons. Moreover, sportsmen who tend to experience sore shoulders, knees, and/or elbows while using Deca experience no pain and the associated pain is primarily due to intense workouts. However, the use of Deca Durabolin for a period of six to eight weeks can almost nullify this problem as the steroid can dramatically improve nitrogen retention and recuperation time between workouts.

Deca Durabolin Improves Immune FunctionIf that was not all, sportsmen who are regular or first-time users of anabolic steroids and worry about skin, scalp, and prostate complications can use this drug without second thoughts as Deca is converted to a less-potent compound by 5 alpha-reductase, the enzyme which converts testosterone to the more-potent DHT. In other words, this anabolic androgenic steroid gets somewhat deactivated in the prostate, skin, and scalp and all these tissues tend to experience an effectively-lower androgen level than other parts of the body that also means that hair loss, prostate complications, and skin problems are very rarely seen with the use of this steroid. In order to reap the optimum advantages of Deca, it is best used with testosterone. It is best used in moderate doses of 400 mg per week and the long life of this steroid makes it best suited to more traditional cycles and not the short alternating cycles.

Friday, February 7, 2014

COMING OFF ANABOLIC STEROID CYCLES

Sure, it’s easy to compile a drug stash, and if you can get past needle phobias, can successfully stack anabolic steroids, and suffer through the side effects of your cycle, you’re doing better than a lot of bodybuilders. But there’s one more hurdle for you to get over… how to come off of your cycle, relatively unscathed.


In the old days (the late 80’s and early 90’s), bodybuilders came off steroids much more often than they do today. A lot of that is because the number of appearances that bodybuilders made in the late 80’s, for instance, were far fewer than the number of appearances they make today. In fact, most pro bodybuilders are gone at least 2 weekends every month in between competitions. If they’re sponsored by or under contract with a major supplement company, they are often on the road far more than that. Because of the number of appearances these days, the pros—and many amateurs—need to remain in good condition, and that necessitates longer drug cycles. The fear that accompanies longer drug cycles is the catabolic phase—the one that will usher in muscle loss, fat gain, slower metabolism, etc.

In the late 80’s, I remember a friend of mine (a popular IFBB pro) who told me that he hadn’t gone off a drug cycle in well over a year. No breaks whatsoever! At that time, staying on a cycle for longer than 16-20 weeks was almost unheard of. So, I was inclined to believe it based on his hair-trigger temper, the quality of his physique (he had a perpetual “androgen sunburn”) and the odd hardness and mottled appearance he displayed.

I asked if staying on that long was messing with his head, and he proceeded to tell me that he had recently experienced suicidal feelings and tendencies. I asked, “Do you think there’s a correlation between being on steroids non-stop, and feeling suicidal, or at least, ‘pent up’?” He said he did, but that he was deathly afraid to go off of a cycle for fear he’d “lose size” and not be competitive enough in the current climate.  Today, that would be an even bigger concern, and the bells and whistles in this guy’s head would be deafening.

Don’t get me wrong, I’m not into telling pathetic cautionary tales, warning against the evils of ‘roids. My honest feeling is that most people can maintain a drug cycle for an extended period of time, and be healthy, if they know what they’re doing. It’s the coming off that is the hard part; whether over a short period of time or a long one. Naturally, coming off after 24 weeks is going to be harder than coming off after 10 weeks. 

Symptoms that follow going off an anabolic steroid cycle include: weight loss, muscle atrophy, loss of body strength, fatty deposits, as well as depression, lack of motivation and discipline and an actual aversion to the gym. In general, symptoms worsen when the individual has been on the cycle for an extended period of time. It’s the proportional kick in the ass!  The body gives back what you give it.

Drug Trade – Why We Make it More Difficult for Ourselves
Part of why people experience side effects in coming off a drug cycle is the fact that they haven’t planned for impending side effects while on the drugs. In other words, they start out planning for a 12 week cycle and choose drugs in combination that would suit that length of time. Once they decide to remain on a longer cycle, however, the game changes and the drugs they have been using during that 3 month cycle aren’t terribly conducive to the longer 18-20 week cycle. When they try to continue with the original drugs they’ve been taking, and extend the time alone, it becomes increasingly difficult to come off in any way that is correct or safe. In my experience, this is when bitch tits occur most often because people miscalculate the half-life of drugs and don’t take enough drugs to counteract aromatization, or to kickstart testosterone production. The latter provides a whole other set of side effects when facilitated improperly. 

Different Drugs…
Resuming testosterone production is the trickiest part of going off of any cycle, but particularly tricky following a long one. All steroids will cause a certain amount of lag in testosterone resumption, but among steroids some are worse than others. For instance, moderate testosterone suppressing drugs such as Primobolan, D-bol, Winstrol or Deca aren’t going to suppress testosterone production as much as hardcore drugs like Testosterone Propionate or Cypionate. However, testosterone suppression shoots up to about 30%-40% after just 10 days on a cycle. That doesn't mean that 100 days will put suppression into the negative zone, because it is not exponential. Testosterone suppression does level off at a certain point, but what happens is that the body’s own production of testosterone takes much longer to resume, the longer that body remains on a cycle. So, a male bodybuilder on a 10 week cycle, for instance, will have less time between cessation of the cycle and resumption of their own testosterone production than someone who stays on a cycle for 20 weeks. This is an important consideration because it dictates how much Clomid and HCG to take in order to get normal testosterone production back. 

Direct Relief
Clomid and HCG are the obvious choices to kickstart testosterone production again, but there are a host of other problems to tackle, too. Let’s first deal with this combination of drugs and then move on to some others that will help bridge the gap between your cycle and life off steroids. In order to re-start or increase the body's own testosterone production, doses of HCG are necessary. Essentially, what HCG does is directly and rapidly stimulate the testes’ Leydig’s cells. This is where testosterone production begins. But Clomid is also necessary because it completes the hypothalamohypophysial testicular axis. But Clomid therapy must begin prior to HCG therapy since it takes longer to become effective and has a great deal to do with half-life of steroids ingested over the period of time in question.
Roughly, this is approximately what a bodybuilder/ athlete should inject:

Administration of HCG: Middle of the last week of discontinuance of anabolic steroids
                                   5000i.u./ per day x 3 days (total: 3 days)
                                   5000i.u./every 5 days x 3 shots (total: 15 days)

The administration of Clomid is taken over the course of 2 weeks, and usually after HCG therapy begins:
                                   Two-50mg tablets/day x 7 days
                                   One-50mg tablet/ day x 7 days

Note: For those people who remain on cycles for longer than 12 weeks, I always recommend HCG injections that are a little more frequent in the last 15 days. I recommend 5 shots, in fact, rather than 3. I also recommend for everyone that they take additional steps to see that their exit from a cycle is a smooth and graceful one.

A Graceful Exit
Gracefully exiting a cycle in a general sense is listed above. But there is little information out there on other ways to bridge the gap between being full of anabolic steroids and being free of them. One thing you need to get over, however, before ever starting a cycle, is the notion that you can actually ameliorate symptoms by using natural means. Sure, these ergogenic aids can’t hurt you, but you’re going to be wasting money that you could be spending on legitimate non-steroidal chemical bridges, such as Cytadren, Clenbuterol and Cytomel.

Cytadren: It reduces cortisol levels exceedingly well just following the completion of a cycle. Typically, athletes will cycle it and gradually go from higher doses down to low doses in the hope to let the body’s production of cortisol trickle in slowly until the body becomes accustomed to it. Elevated cortisol levels are, of course, associated with a lot of undesirable symptoms, such as loss of strength, loss of muscle size, and fatty deposits. Typically, a 2-4 week cycle of Cytadren is common. Dose depends upon length of time on cycle, weight of athlete and other pharmaceuticals being used in conjunction.

Clenbuterol: This is also a successful cortisol blocker, and can and should be used in conjunction with Cytadren. Clenbuterol can also contribute to increases in strength gains or, in the case of a person just exiting a cycle, maintain current strength relatively well. Keeping fat stores at bay after stopping a cycle can also be an issue, but Clenbuterol can help athletes remain lean. Begin taking Clenbuterol about 1-2 weeks prior to cessation of the cycle, to overlap and ‘bridge’ the gap between the anabolic steroid cycle and the weeks that will be spent ‘resting’. Usually, I recommend people stay on Clenbuterol for about 8-10 weeks, including the overlapped time.

Cytomel: Many athletes take Cytomel in an effort to drop fat prior to a competition. This is a fairly serious investment in a potential future of obligatory intake of something for life. I do think it has its place after a cycle, however, because it can smooth rough edges of a metabolic rate that will inevitably dip below normal once the cycle has ended. I don’t advocate its use for women as much as for men, but if either feel the need to take it, take no more than 25-40mcg daily for no more than 30 days. Taper off by cutting pills in half until you are down to a few days of 12.5mcg at the end.

Thursday, January 23, 2014

High Testosterone

From magazine adds to TV commercials, with increasingly regularity you hear talk of those suffering from low testosterone. You’ve seen the commercials talking about “Low-T” and the treatment of the condition, but what about high testosterone, what about those suffering from high testosterone? Let’s be clear, if you’re a man with high testosterone you’re not suffering, in-fact, your quality of life is more than likely far greater than the man next to you. To understand this, we only need to understand two things, what testosterone is and what happens when our levels fall. Once we understand these two simple, very simple things, then we can have a grasp on what high testosterone can do for you.
Understanding Testosterone

Testosterone is the primary male hormone, the primary androgen, and by its nature is responsible for male sexual development and the male characteristics. While testosterone is the primary male hormone it is also produced by women, although in far lesser amounts. In either case, with men and women testosterone is essential to our health and function; men simply require more, about ten times the amount. By design, testosterone affects both our physical and mental state, as well as our overall sexual function.
Low Testosterone

Millions upon millions of men worldwide suffer from low testosterone; in the U.S. alone it is estimated to be between 15-20 million. Many women suffer from testosterone related issues too; women who are on birth control often find their levels suppressed, and post-menopausal women often find they have a problem. Even so, it will be men who carry the brunt of the weight and when levels fall rest assured it is no fun for anyone. Low testosterone can cause many unwanted symptoms, including but not limited to:

Loss of Libido

Erectile Dysfunction

Loss of Muscle Mass

Loss of Strength

Depression

Increased Body-Fat

Inability to Lose Body-Fat

Loss of Focus

Loss of Energy

Insomnia

Lethargy
The Reverse

When we have high testosterone levels, we can take the list above and completely flip it around. When we have high testosterone levels, not only will the above symptoms never occur, but regarding each one that area of our life will be improved upon. No, this does not automatically mean those with high testosterone will be behemoths of muscle and strength, training and diet will still dictate this end. However, men with high testosterone will be in better shape, enjoy a higher quality of life and simply possess a better sense of well-being. Men with high levels can expect the following:

Increased Muscle Mass

Increased Strength

Decreased Body-Fat

Increased Clarity of Thought

Increased Energy

Enhanced Mood

Increased Libido

Better Rest

Increased Rate of Recovery

Obtaining High Levels

There is no set in stone normal testosterone level. As individuals, we all produce varying amounts of the hormone, and the amounts naturally produced can vary dramatically from person to person. In any case, in most therapeutic circles a total testosterone reading of 300ng/dl or below is considered low with anywhere from 500ng/dl-700ng/dl being considered adequate. As you can see, that’s quite a variation.

In any case, we can describe high testosterone as any amount above your baseline average, and to obtain it there is only one true way; anabolic steroids. If you desire high testosterone levels you will need to supplement with the primary anabolic steroid testosterone. If you need more gas in your car then guess what, you need to put gas in the car, and if you want more testosterone in the body you’re going to have to give the body testosterone. There are certain foods you can eat that will naturally stimulate production and there are a few testosterone boosting supplements, but to obtain true high levels, pure exogenous testosterone is the only way.